Purpose: This study aims to develop a self-reflection program for nurses who have experienced the death of pediatric patients in the intensivecare unit and to evaluate its effectiveness. Methods: The self-reflection program was developed by means of the following four steps: establishmentof the goal through investigation of an initial request, drawing up the program, preliminary research, and implementation and improvementof the program. The study employed a methodological triangulation to evaluate the effectiveness of the program. Participants were 38 nurseswho had experienced the death of pediatric patients (experimental group=15, control group=23); they were recruited using convenience sampling. The self-reflection program was provided over 6 weeks (6 sessions). Data were collected from April to August, 2014 and analyzed using ttestsand content analysis. Results: The quantitative results showed that changes in personal growth (t=-6.33, p qqqlt;.001) and burnout scores(z=-2.76, p=.005) were better in the experimental group compared to the control group. The qualitative results exhibited two themes, namely“personal growth” and “professional growth”, and ten sub-themes. Conclusion: The self-reflection program developed by this study was effectivein helping nurses who had experienced the death of pediatric patients to achieve personal growth through self-reflection, and it was confirmedthat the program can be applied in a realistic clinical nursing setting. Furthermore, it can be recommended as an intervention program for clinicalnurses.