Purpose: The purpose of this study was to identify which nursing interventions are the most effective in fall prevention for hospitalizedpatients. Methods: From 3,675 papers searched, 34 were selected for inclusion in the meta-analysis. Number of fallers, falls,falls per 1,000 hospital-days, and injurious falls, fall protection activity, knowledge related to falls, and self-efficacy about falls wereevaluated as outcome variables. Data were analyzed using the Comprehensive Meta Analysis (CMA) 2.2 Version program and the effectsizes were shown as the Odd Ratio (OR) and Hedges’s g. Results: Overall effect size of nursing interventions for fall preventionwas OR=0.64 (95% CI: 0.57∼0.73, p qqqlt;.05) and Hedges’s g= - 0.24. The effect sizes (OR) of each intervention ranged from 0.34 to0.93, and the most effective nursing intervention was the education qqqamp; environment intervention (OR=0.34, 95% CI: 0.28∼0.42,p qqqlt;.001), followed by education intervention (OR=0.57, 95% CI: 0.50∼0.67, p =.001). Subgroup analyses showed that multifacetedinterventions (OR=0.76, 95% CI: 0.73∼0.79, p qqqlt;.001) were more effective than unifactorial interventions, and that activities for preventionof falls (OR=0.08, 95% CI: 0.05∼0.15, p qqqlt;.001) showed the largest effect size among outcome variables. Conclusion: Fallsin hospitalized patients can be effectively prevented using the nursing interventions identified in this study. These findings providescientific evidence for developing and using effective nursing interventions to improve the safety of hospitalized patients.