Purpose: The purpose of this study was to examine a Korean Mindfulness Based Stress Reduction (K-MBSR) program for middle agedwomen and to verify the program’s effectiveness on stress, stress coping style, depression, anger and sleep. Methods: Fifty-twowomen aged from 40 to 59 (26 in the experimental group and 26 in the control group) from G city participated in the study. Datawere collected from February 13 to April 3, 2013. The experimental group received 8 sessions, scheduled once a week, with eachsession lasting two and a half hours. Outcome variables included stress, stress coping style, depression, anger, sleep and a physiologicalmeasure (EEG). Results: There were significant decreases for stress (t= - 2.14, p =.037), depression (t= - 2.64, p =.011), state traitanger (t= - 3.79, p qqqlt;.001) in the experimental group compared to the control group. Conclusion: The findings in this study indicatethat the K-MBSR program is an effective program to decrease stress, depression, and state trait anger in middle aged women.