Objectives: The purpose of the study was to find determinants for participation in the National health screening program participation according to sex in Korean. Methods: Data for 5,355 from the Korea National Health and Nutrition Examination Survey Ⅵ was included. Impact factors were analyzed by sex using logistic regression. Results: The participation in men rates(65.6%) higher than women(60.6%). In the case of men, those who have higher age (OR=0.33, 95% CI 0.21-0.52), higher income(OR=0.72, 95% CI 0.54-0.97), higher education (OR=0.54, 95% CI 0.36-0.81), occupation(OR=1.80, 95% CI 1.38-2.36), spouse(OR=1.95, 95% CI 1.45-2.62) were shown to have health examination more frequently. In the case of women, those who live in more developed city(OR=1.42, 95% CI 1.1-1.76), have higher age(OR=0.17, 95% CI 0.11-0.26), higher income(OR=0.17, 95% CI 0.11-0.26), higher education(OR=0.68, CI 0.46-0.99), occupation(OR=1.54, CI 1.32-1.80) and health insurance(OR=2.68, 95% CI 1.17-6-15) were shown to have health examination more frequently insurance were shown to have health examination more frequently. Conclusions: As a result, for both, age, income, education and occupation influenced health examination rate. Additionally, for men, marital status and for women, residence and the type of their health insurance was influenced. Individualized intervention is needed to increase participation rate.