The purpose of this study are to find out the gender and school level differences in adolescents’ depression , and the influences of parent attachment and school stress on adolescents’ depression and the effect of ego-resilience relations between parent attachment and depression, and that of school stress and depression. 402 of students(the first and the second graders of middle school and of high school in academic track in D area) completed questionnaire on parent attachment, school stress, ego-resilience, and depression. Descriptive statistic analyses, reliability analyses, Two-way ANOVAs, correlation analyses, and hierarchial multiple regression analyses were conducted through SPSS WIN 20.0. The findings are as follows. 1) There was school level difference, but not gender differences, on adolescents’depression. 2) There was ego-resilience control effect on the relations between parent attachment and adolescents’ depression only for middle school students, but not for high school students. 3) There were ego-resilience control effect on the relations between school stress and adolescents’ depression for both middle and high school students. The importance of ego-resilience and school levels in understanding adolescents’ depression was discussed.