Purpose: The aim of this study was to develop and measure the effect of a movie-based-nursing intervention program designed to enhance motivationfor rehabilitation and reduce depression levels in stroke patients. Methods: The study used a quasi-experimental, nonequivalent controlgroup and a pretest-posttest design. The 60 research subjects were assigned to the experimental (n=30) or control group (n=30). The moviebasednursing intervention program was provided for the experimental group during 60-minute sessions held once per week for 10 weeks. Theprogram consisted of patient education to strengthen motivation for rehabilitation and reduce depression, watching movies to identify role models,and group discussion to facilitate therapeutic interaction. Results: After 10 weeks of participation in the movie-based nursing interventionprogram, the experimental group’s rehabilitation motivation score was significantly higher, F=1161.54 (within groups df=49, between groupsdf=1), pqqqlt;.001, relative to that observed in the control group. In addition, the experimental group’s depression score was significantly lower relativeto that observed in the control group, F=258.97 (within groups df=49, between groups df=1), pqqqlt;.001. Conclusion: The movie-based nursingintervention program could be used for stroke patients experiencing psychological difficulties including reduced motivation for rehabilitation andincreased depression during the rehabilitation process.