Purpose: The process of designing a questionnaire is complicated. Many questionnaires on nursing phenomena have been developedand used by nursing researchers. The purpose of this paper was to discuss questionnaire design and factors that should beconsidered when using existing scales. Methods: Methodological issues were discussed, such as factors in the design of questions,steps in developing questionnaires, wording and formatting methods for items, and administrations methods. How to use existingscales, how to facilitate cultural adaptation, and how to prevent socially desirable responding were discussed. Moreover, the triangulationmethod in questionnaire development was introduced. Results: Steps were recommended for designing questions such asappropriately operationalizing key concepts for the target population, clearly formatting response options, generating items andconfirming final items through face or content validity, sufficiently piloting the questionnaire using item analysis, demonstrating reliabilityand validity, finalizing the scale, and training the administrator. Psychometric properties and cultural equivalence should beevaluated prior to administration when using an existing questionnaire and performing cultural adaptation. Conclusion: In the contextof well-defined nursing phenomena, logical and systematic methods will contribute to the development of simple and precisequestionnaires.