Purpose: This study was done to develop an evidence-based incontinence care protocol through an adaptation process and to evaluatethe effects of the protocol. Methods: The protocol was developed according to the guideline of adaptation. A non-randomizedcontrolled trial was used for testing the effects of the new Incontinence Care Protocol. A total of 120 patients having bowel incontinencewith Bristol stool type 5, 6, and 7 and admitted to intensive care units were recruited to this study. The newly developed incontinencecare protocol was used with patients in the experimental group and conventional skin care was given to patients in thecontrol group. Outcome variables were incontinence-associated dermatitis (IAD) severity, pressure ulcer occurrence and severity. Results: The experimental group had significantly less severe IAD (t=6.69, pqqqlt;.001), lower occurrence of pressure ulcers (χ 2=7.35,p=.007), and less severity of pressure ulcers (Mann-Whitney=86.00, p=.009) than the control group. Conclusion: Use of this incontinencecare protocol has the effects of preventing pressure ulcers and inhibiting worsening of IAD and pressure ulcers. Therefore,this incontinence care protocol is expected to contribute to managing IAD and pressure ulcers.