Purpose: The purpose of this study was to examine the moderating mediation effect of self-esteem on the relations among adolescents’abuse experiences, depression and anxiety, and suicidal ideation. Methods: The participants were selected using secondarydata from a population in the 2012 Korea Welfare Panel Survey (KOWEPS). Data were analyzed using SPSS 15.0 and SPSS Macro,and bootstrapping and hierarchical regression analysis were performed to analyze multilevel models. Results: First, analysis of themediating effect of the adolescents’ abuse showed that there was significant mediating influence between suicidal ideation and depressionand anxiety. Second, hierarchical regression analysis showed that self-esteem had significant mediation effect on depressionand anxiety in adolescents’ suicidal ideation. Third, SPSS Macro showed that self-esteem also significantly moderated the mediatingeffect of adolescents’ abuse experiences on suicidal ideation through depression and anxiety. Conclusion: The study results suggestthat in future research on adolescent’s abuse experience, the risk of suicide in depression and anxiety scores should be selectedthrough evaluation of each individual’s self-esteem scale. Coping strategies with immediate early intervention should be suggested.