[영문]Objectives. This study examined whether the association between obesityand 12-month prevalence of major depressive disorder (MDD) varied accordingto racial/ethnic status and nativity in representative national samples ofblack, Latino, Asian, and non-Hispanic white people.Methods. We used data from the Comprehensive Psychiatric EpidemiologySurveys.Results. In analyses by gender, obesity was associated with an elevatedrisk of MDD among non-Hispanic white women (adjusted odds ratio[AOR] =1.73; 95% confidence interval [CI] 1.27, 2.35; p50.001). Formal testfor interaction revealed significant variation by race present between non-Hispanic white women and black, Latin, and Asian women. No significantdifferences were evident among men. In analyses by nativity, the associationbetween obesity and MDD was significant among U.S.-born non-Hispanicwhite women (AOR51.62; 95% CI 1.16, 2.27; p50.001) and U.S.-born blackwomen (AOR51.29; 95% CI 1.01, 1.66; p50.041). Significant interactionswere present among U.S.-born white and black women, Latin women, andAsian women. No significant interactions were evident among foreign-bornwomen. Similarly, no significant differences were present among native-bornor foreign-born men.Conclusions. The findings suggest that the association between obesity andMDD varies according to racial/ethnic status and nativity. Understandingthe link between obesity and depression may be imperative to designinginterventions to address body weight maintenance and reduction strategiesamong women.