[영문]Purpose. The associations between pharmacist-managed antimicrobial prophylaxis in Medicare patients who had surgical codes indicative of the need for antimicrobial prophylaxis and the major health care outcomes of death rate, length of stay, Medicare charges, drug charges, laboratory charges, and complications were explored. Methods. Pharmacist management of antimicrobial prophylaxis was evaluated in 242,704 Medicare patients from 806 hospitals. Results. Patients who developed a surgical-site infection (SSI) had a 331.58% increased risk of death compared with patients who did not develop an SSI (2 = 743.471; df = 1; p qqqlt; 0.0001; odds ratio [OR], 3.62; 95% confidence interval [CI], 3.28?3.99). Patients who developed an SSI also had a 167.16% increase in length of stay, 136.49% increase in total Medicare charges, 245.96% increase in drug charges, and 187.14% increase in laboratory charges. In hospitals without pharmacist-managed antimicrobial prophylaxis, death rates were 52.06% higher (105 excess deaths; p qqqlt; 0.0001; OR, 1.54; 95% CI, 1.46?1.63), length of stay was 10.21% higher (167,941 excess patient days, p qqqlt; 0.0001), mean ± S.D. total Medicare charges were 3.10% higher (