Objectives: This study is aimed at exploring the temporal developmental relationship of adolescent depression and parents’ child-rearing attitudes, and to examine gender differences in the relationship. The middle school students of the 2011-2013 1st Korea Children and Youth Panel data were used for analysis and the sample consisted of 2.073 individuals. Methods: Research questions were answered through the Latent Growth Model and Autoregressive Cross-Lagged Model. Results: As the results of the Latent Growth Model show, adolescent depression declines as time goes by and there are differences in the depression felt by individuals. An autoregressive cross-lagged model and multiple group analysis were executed by gender. The results show significant gender differences in the relationship between depression and Parents’ child-rearing attitudes. Parental neglect has shown differences influencing adolescents depression between males and females. However, in case of parental abuse, no differences between males and females were observed. Conclusion: The results of this study imply that the policy on depression should be carefully considered when preparing for interventions targeting adolescents by gender.